We ended up staying at this hotel when booking a trip through lastminute.com - its a great hotel well located less than five minutes from the main station (haupbahhof).
The room was very pleasant - reasonably sized and warm, standard facilities of ensuite and television with satellite. Good double glazing - although we were overlooking a busy road we didnt hear anything. Standard of cleanliness and decoration seemed to be high.
The breakfast in the morning was very good - a standard hotel buffet type thing (pastries, fruit, yoghurt, rolls, cooked options etc etc) - and the staff were very friendly and helpful when we needed them All in all I would thoroughly recommend this hotel.
We arrived at the hauptbahnhof at about 10pm and found it hard initially to find the hotel even though we knew it was located within 200 metres of the station. My tip is head for the Hauptbahnhof Nord exit (where the Lufhansa airport buses pick up from) and then head out of the station and turn left at the Eden Hotel - the Regent is on the next corner about 100metres to the left.











